5 Pharmaceutical preparations, biological preparations, and cell- and gene-based therapy products to prevent and treat age-related cardiovascular disease, neurodegenerative disease, musculoskeletal disease, pulmonary disease, metabolic disease, diseases of the liver, macular degeneration and other ocular diseases, kidney disease, and cancer; pharmaceutical preparations, biological preparations, and cell- and gene-based therapy products to prevent and treat cardiovascular disease, neurodegenerative disease, musculoskeletal disease, pulmonary disease, metabolic disease, diseases of the liver, macular degeneration and other ocular diseases, kidney disease, and cancer