5 Medicinal and biological preparations for pharmaceutical, clinical or medical treatment, namely, preparations for the modulation of gene and protein expression working at DNA transcription, RNA translation and/or degradation processes related thereto for the treatment of cardiovascular diseases, metabolic diseases, overweight, obesity, diabetes mellitus, dyslipidemia, liver steatosis (fatty liver disease), steatohepatitis, non-alcoholic fatty liver disease, metabolic-associated fatty liver disease, atherosclerosis, chronic visceral inflammation, ovarian cancer and related diseases and disorders