5 Pharmaceutical preparations and therapeutic agents for use in the treatment and prevention of neurodegenerative diseases, cancer, metabolic disease, auto-immune diseases, inflammation, infectious disease, prion-based diseases, cardiovascular diseases, women's health in the nature of uterine fibroids and Polycystic Ovary Syndrome (PCOS), renal disease, pulmonary diseases, neurological disease, fibrosis, liver diseases and wound healing; Reagents for medical use; Reagents for clinical use in the nature of clinical medical use