5 Dietary supplements; Dietary supplements consisting primarily of Leucine, resveratrol, and pyridoxine; Dietary supplements for humans; Dietary supplements for improvement of endogenous NAD+ utilization, activation of SIRT1 and AMPK, increase of mitochondrial biogenesis, increase of fat oxidation and decrease in insulin resistance; Dietary supplements in the form of capsules; Dietary and nutritional supplements; Dietary and nutritional supplements containing Leucine, resveratrol, and pyridoxine; Nutraceuticals for use as a dietary supplement for improvement of endogenous NAD+ utilization, activation of SIRT1 and AMPK, increase of mitochondrial biogenesis, increase of fat oxidation and decrease in insulin resistance