5 Pharmaceutical preparations, biological preparations, and cell- and gene-based therapy products to prevent and treat age-related cardiovascular disease, neurodegenerative disease, musculoskeletal disease, pulmonary disease, metabolic disease, diseases of the liver, macular degeneration and other ocular diseases, kidney disease, and cancer; pharmaceutical preparations, biological preparations, and cell- and gene-based therapy products to prevent and treat age-related cardiovascular disease, neurodegenerative disease, musculoskeletal disease, pulmonary disease, metabolic disease, diseases of the liver, macular degeneration and other ocular diseases, kidney disease, and cancer