5 Reagents for medical use; Biological preparations for the treatment of eye diseases, hemoglobinopathy, cancer, nervous system diseases, pulmonary fibrosis, cardiomyopathy, dyslipidemia; Pharmaceutical preparations for the treatment of eye diseases, hemoglobinopathy, cancer, nervous system diseases, pulmonary fibrosis, cardiomyopathy, dyslipidemia; stem cells for medical purposes; pharmaceutical and biological preparations based on gene, genome and cellular editing, modulation, modification, engineering, regulation, repair and therapy for use in human therapeutics