5 Pharmaceuticals, medical, biological or biochemical preparations, substances for the treatment of diseases, as well as preparations for medical treatments, in particular, antibodies and derivatives being monoclonal antibodies, bispecific antibodies, multispecific antibodies, antibody fragments, single-chain variable fragments, di-scFv or light and heavy chains of antibodies for medical purposes, bifunctional or multifunctional proteins being T-cell engagers or NK cell engagers for medical purposes with binding affinity to immune cells, in particular NK cells, and other reagents for the diagnosis, prevention, monitoring and treatment of diseases, in particular cancers, infectious diseases, inflammatory diseases, and other immune pathologies