5 Extracellular vesicles, namely, exosomes, for medical use; extracellular vesicles for clinical use; biological preparations comprising extracellular vesicles known as exosomes for therapeutic applications; living cells for medical purposes; pharmaceutical preparations and substances; dermatological preparations; pharmaceutical preparations for the treatment of cells; pharmaceutical preparations, namely, a drug delivery system comprising genetically (engineered) purified extracellular vesicles for therapeutic use; pharmaceutical preparations, namely, extracellular vesicles to deliver protein or RNA for genetic therapy; extracellular vesicles used as materials for pharmaceutical products; biological preparations for medical purposes; biological preparations comprising extracellular vesicles; biological preparations comprising a therapeutic target protein-loaded extracellular vesicles; biological preparations comprising extracellular vesicles for pharmaceutical purposes; biological reagents for medical use; medical preparations and articles; none of the aforesaid products being for use in relation to ultrasound-based medical, diagnostic or therapeutic imaging apparatus or devices used for medical, diagnostic or therapeutic imaging and related software.