5 Pharmaceutical preparations for use in the treatment of fibrosis, inflammatory and autoimmune disorders, metabolic diseases, cardiovascular diseases, liver fibrosis, kidney fibrosis, pulmonary fibrosis, vascular fibrosis and cardiac fibrosis; pharmaceutical preparations for use in the treatment of systemic sclerosis, Sjogren's syndrome, Rheumatoid arthritis, and systemic lupus erythematosus; pharmaceutical preparations for use in the treatment of cancer and radiation induced lung injury; pharmaceutical preparations for use in the treatment of idiopathic pulmonary fibrosis, and pulmonary arterial hypertension; pharmaceutical preparations for use in the treatment of nonalcoholic steatohepatitis (NASH), fatty liver diseases and disorders and steatohepatitis and other related diseases and disorders