5 Antibodies, proteins, T cell proteins and peptides for medical use, monoclonal antibodies for clinical or medical use, pharmaceutical and biochemical substances and preparations, namely, small molecules, CD8O antagonists for the treatment of cancer, rheumatoid arthritis and auto-immune diseases; in vivo immunotherapeutic, immunoprophylactic and immunodiagnostic agents, preparations and substances for clinical or medical use; vaccines; protein conjugates; diagnostic and analytical preparations for medical and veterinary use, namely, products to diagnose and analyze tissue damage caused by inflammation due to auto-immune diseases; enzymes and enzyme preparations for clinical or medical use and the treatment of cancer, rheumatoid arthritis and auto-immune diseases; chemical products for use in medical science, namely, T-cell receptors, small molecule and protein therapeutics