5 Pharmaceuticals for the treatment of inflammatory diseases including arthritis, psoriasis and vasculitis, cardiovascular diseases including myocardial infarction, congestive heart failure, atherosclerosis and stroke, metabolic diseases such as diabetes, cancer, neurodegenerative diseases such as multiple sclerosis, infectious diseases including bacterial, viral and parasitic diseases, and for use in organ transplantation; pharmaceuticals, namely protein therapeutic agents for the treatment of the aforesaid diseases, and for use in organ transplantation; pharmaceuticals, namely, prodrugs for the treatment of the aforesaid diseases and for use in organ transplantation; pharmaceuticals, namely polypeptides for the treatment of the aforesaid diseases and for use in organ transplantation; veterinary preparations for the treatment of inflammation, cancer and infectious diseases in pets and in livestock