In the statement, Column1, line 6, after the word metabolites, "PROSTAGLANDINS AND " should be inserted, In the statement Column 2, line 10 , "OWNER OF ENGLAND " should be deleted, and "OWNER OF EUROPEAN COMMUNITY TRADEMARK " should be inserted, and , In the statement, Column 2, line 11, " EXPIRES 4-25-2004 " should be deleted ,and "EXPIRES 4-25-2007, should be inserted.